. 2022; 32(1): 131-141 | DOI: 10.4274/terh.galenos.2021.22599 | ||||
Evaluation of JAK/STAT Signaling Pathway-associated Protein Expression at Implantation Period: An Immunohistochemical Study in RatsCan Köse1, Seda Vatansever2, Sevinç İnan3, Cengiz Kırmaz4, Çevik Gürel6, Derya Erışık5, Gökçe Ceren Kuşçu5, Kemal Özbilgin21University of Health Sciences Turkey, İzmir Tepecik Education and Research Hospital, Clinic of In Vitro Fertilization Unit, İzmir, Turkey2Manisa Celal Bayar University Faculty of Medicine, Department of Histology and Embryology, Manisa, Turkey 3İzmir University of Economics Faculty of Medicine, Department of Histology and Embryology, İzmir, Turkey 4Manisa Celal Bayar University Faculty of Medicine, Department of Internal Medicine, Manisa, Turkey 5Ege University Faculty of Medicine, Department of Histology and Embryology, İzmir, Turkey 6Harran University Faculty of Medicine, Department of Histology and Embryology, Şanlıurfa, Turkey Objective: The implantation period of gestation is a complex process in which numerous molecular pathways play a role. The Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of the evolutionarily conserved cascades used to transduce a multitude signals for several biological events such as implantation and uterine receptivity. Previous studies have indicated that the implantation process is disrupted by the lack of proteins involved in this pathway. However, our literature knowledge showed that there is no study evaluated the expression of JAK/STAT signaling pathway-associated proteins during the implantation period. This study investigated the expression patterns of JAK/STAT signaling pathway-associated proteins in rats by immunohistochemical (IHC) staining according to gestational days. Can Köse, Seda Vatansever, Sevinç İnan, Cengiz Kırmaz, Çevik Gürel, Derya Erışık, Gökçe Ceren Kuşçu, Kemal Özbilgin. Evaluation of JAK/STAT Signaling Pathway-associated Protein Expression at Implantation Period: An Immunohistochemical Study in Rats. . 2022; 32(1): 131-141 Sorumlu Yazar: Gökçe Ceren Kuşçu, Türkiye |
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