Periorbital lupus erythematosus profundus: A case report and review of the literature
Didem Mullaaziz1, Serap Maden1, Orgun Deren2, Hanife Özkayalar31Near East University Faculty of Medicine, Department of Dermatology and Venereology, Nicosia, Cyprus2Near East University Faculty of Medicine, Department of Plastic and Reconstructive Surgery, Nicosia, Cyprus
3Near East University Faculty of Medicine, Department of Pathology, Nicosia, Cyprus
Lupus erythematosus profundus (LEP), is a rare form of, chronic cutaneous LE, also called lupus erythematosus panniculitis. LEP is characterized by subcutaneous fatty tissue involvement spesifically in patients with LE. Before systemic LE was diagnosed, very few reports reported the presence of lesions of lupus erythematosus profundus. The rare manifestations of the disease are remarkable with the unusual features of the cases. A 43-year-old female patient diagnosed with bilateral periorbital LEP was presented and the literature was reviewed. Significant clinical improvement was achieved in the patient who was given systemic hydroxychloroquine and topical pimecrolimus therapy. This report suggests that asymptomatic periorbital erythema and edema may develop as a manifestation of LEP.
Keywords: Lupus erythematosus, lupus erythematosus profundus, lupus panniculitis, orbital areaPeriorbital lupus eritematozus profundus: Bir olgu sunumu ve literatürün gözden geçirilmesi
Didem Mullaaziz1, Serap Maden1, Orgun Deren2, Hanife Özkayalar31Near East University Faculty of Medicine, Department of Dermatology and Venereology, Nicosia, Cyprus2Near East University Faculty of Medicine, Department of Plastic and Reconstructive Surgery, Nicosia, Cyprus
3Near East University Faculty of Medicine, Department of Pathology, Nicosia, Cyprus
Lupus eritematozus profundus (LEP), nadir görülen bir kronik kutanöz lupus eritematozus türü olup, lupus eritematozus panniküliti olarak da adlandırılmaktadır. LEP, LE hastalarında spesifik olarak subkutan yağ doku tutulumu ile karakterizedir. Sistemik lupus eritematozus tanısı konulmadan önce LEP lezyonlarının varlığını bildiren çok az sayıda rapor bildirilmiştir. Hastalığın nadir görülen bulguları, olguların sıra dışı özellikleri ile dikkat çekici olmaktadır. Burada bilateral periorbital LEP tanısı konulan, 43 yaşında bir kadın olgu sunulmuş ve literatür gözden geçirilmiştir. Sistemik hidroksiklorokin ve topikal pimekrolimus tedavisi verilen hastada anlamlı klinik iyileşme sağlanmıştır. Bu rapor, asemptomatik periorbital eritem ve ödemin LEP’nin bir bulgusu olarak gelişebileceğini desteklemektedir.
Anahtar Kelimeler: Lupus eritematozus, lupus eritematozus profundus, lupus panniküliti, orbital alanCorresponding Author: Didem Mullaaziz, Türkiye
| TOOLS |
 Full Text PDF English Full Text Print Download citation RIS EndNote BibTex Medlars Procite Reference Manager Share with email Share Send email to author
Similar articles Google Scholar |