Antioxidant Properties and Phenolic Composition of Salvia virgata Jacq.
Gökçe Şeker Karatoprak1, Selen İlgün2, Müberra Koşar11Erciyes University, Faculty of Pharmacy, Department of Pharmacognosy, 38039 Melikgazi, Kayseri/TURKEY2Erciyes University, Faculty of Pharmacy, Department of Pharmaceutical Botany, 38039 Melikgazi, Kayseri/TURKEY
Methanol and water extracts of Salvia virgata Jacq. aerial parts were examined for its phenolic contents and antioxidant activities. Both extracts were investigated for their total phenolic contents, total flavonoids and flavonols, qualitative-quantitative compositions (by HPLC-PDA analysis). Free radical scavenging activities (using DPPH● and ABTS●+), iron(II) chelation activity and also the peroxidation level was determined by TBA method. The antioxidant activity of extracts were given as IC50 values and compared with standards; butylated hydoxyanisole, butylated hydoxytoluene, rosmarinic acid, ascorbic acid, and gallic acid. Methanol extract was found to be active for DPPH● radical scavenging activity where as water extract was more active for ABTS●+ radical scavenging. The methanol extract enriched in phenolic compound and rosmarinic acid as the main component in both extracts has been identified
Keywords: Salvia virgata, Antioxidant Activity, HPLCSalvia virgata Jacq.’ın antioksidan özellikleri ve fenolik içeriği
Gökçe Şeker Karatoprak1, Selen İlgün2, Müberra Koşar11Erciyes University, Faculty of Pharmacy, Department of Pharmacognosy, 38039 Melikgazi, Kayseri/TURKEY2Erciyes University, Faculty of Pharmacy, Department of Pharmaceutical Botany, 38039 Melikgazi, Kayseri/TURKEY
Salvia virgata Jacq.’ın toprak üstü kısımlarının metanol ve su ekstresinin fenolik içeriği ve antioksidan özellikleri belirlenmiştir. Her iki ekstrenin de toplam fenolik, toplam flavonoit ve flavonol içeriği, kalitatif-kantitatif kompozisyonları (YBSK ile), serbest radikal süpürücü aktiviteleri (DPPH● ve ABTS●+), demir(II) ile şelat oluşumu ve TBA yöntemi ile peroksidasyon seviyeleri incelenmiştir. IC50 değeri olarak verilen antioksidan aktiviteler butil hidroksianisol, butil hidroksitoluen, rozmarinik asit, askorbik asit ve gallik asit standartları ile karşılaştırılmıştır. Metanol ekstresi DPPH● radikalini süpürücü etkide aktif bulunurken, su ekstresi ABTS●+ radikalini süpürücü etkide aktif bulunmuştur. Metanol ektresinin fenolik bileşiminin daha zengin olduğu ve her iki ekstrede de rozmarinik asitin ana bileşen olduğu tespit edilmiştir.
Anahtar Kelimeler: Salvia virgata, Antioksidan Aktivite, YBSKCorresponding Author: Gökçe Şeker Karatoprak, Türkiye
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