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Development of discriminative and biorelevant dissolution test method for atorvastatin /fenofibrate combination with appliance of derivative spectrophotometry.Panukumar Durga Anumolu, Sunitha Gurrala, Subrahmanyam Chavali Venkata Satya, Santoshi Vani Polisetty, Anjana Ravindran, Radhagayathri AchantaGokaraju Rangaraju College Of Pharmacy, Department Of Pharmaceutical Analysis Osmania University, Hyderabad, Telangana, IndiaINTRODUCTION: Now a days, market is flooded with combination of drugs in various dosage forms, but lack of official methods to quantify them. A single dissolution test method for the analysis of combined dosage form is preferred for simplification of quality control testing. If the developed dissolution medium mimics the bio-relevant and discriminating dissolution procedure for drug products with limited drug aqueous solubility is a useful tool for qualitative forecasting of in-vivo behavior of formulations. Panukumar Durga Anumolu, Sunitha Gurrala, Subrahmanyam Chavali Venkata Satya, Santoshi Vani Polisetty, Anjana Ravindran, Radhagayathri Achanta. Development of discriminative and biorelevant dissolution test method for atorvastatin /fenofibrate combination with appliance of derivative spectrophotometry.. . 2019; 16(1): 0-0 Corresponding Author: Panukumar Durga Anumolu, India |
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