. 2021; 18(3): 0-0 | |||
A Meta-Analysis for Frequency of Intrauterine Growth Restriction and Preterm Premature Rupture of the Membranes in Pregnant Women with COVID-19Reza Bahrami1, David Alan Schwartz2, Mojgan Karimi-Zarchi3, Atiyeh Javaheri4, Seyed Alireza Dastgheib5, Farzad Ferdosian6, Mahmood Noorishadkam7, Seyed Reza Mirjalili7, Hossein Neamatzadeh81Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran2Department of Pathology, Medical College of Georgia, Augusta, GA, USA 3Department of Obstetrics and Gynecology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran 4Department of Obstetrics and Gynecology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran 5Department of Medical Genetics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran 6Children Growth Disorder Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran 7Mother and Newborn Health Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran 8Department of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran The impact of SARS-CoV-2 in pregnancy remains to be determined. Some studies indicated that SARS-CoV-2 infection might be associated with higher risk of adverse outcomes in pregnant women. Here, we performed a meta-analysis to estimate the frequency of intrauterine growth restriction (IUGR) and preterm premature rupture of the membranes (PPROM) in pregnant women with COVID-19. A comprehensive search was performed in PubMed, Scopus, SciELO, MedRxiv, and Web of Science to find all relevant studies published before 10 February 2021. Cross-sectional and consecutive case series reporting pregnancy outcomes of COVID-19 in pregnant women were included. A total of 24 studies including 8 studies on IUGR and 16 studies on PPROM were selected. Pooled data showed that the frequency of IUGR and PPROM was 2.6% and 9.9% in infected women with COVID-19, respectively. Stratified analyses by ethnicity showed that the frequency of IUGR was 2.9% and 2.0% in Asian and Caucasian infected pregnant women, respectively. Moreover, the frequency of PPROM was 10.2% and 5.8% in Asian and Caucasian infected pregnant women, respectively. This meta-analysis showed that the frequency of IUGR and PPROM was 2.6% and 9.9% in the infected pregnant women with COVID-19, respectively. However, well-designed, large-scale and multicenter clinical studies are required to improve and validate these results. Keywords: COVID-19, SARS-CoV-2, Pregnancy, Intrauterine Growth Restriction, Preterm Premature Rupture of MembranesReza Bahrami, David Alan Schwartz, Mojgan Karimi-Zarchi, Atiyeh Javaheri, Seyed Alireza Dastgheib, Farzad Ferdosian, Mahmood Noorishadkam, Seyed Reza Mirjalili, Hossein Neamatzadeh. A Meta-Analysis for Frequency of Intrauterine Growth Restriction and Preterm Premature Rupture of the Membranes in Pregnant Women with COVID-19. . 2021; 18(3): 0-0 Corresponding Author: Mojgan Karimi-Zarchi, Iran |
|