Evaluation Of Diabetes In Pregnancy Study Group Of India (DIPSI) Criteria And Carpenter-Coustan Criteria For Diagnosis Of Gestational Diabetes Mellitus

INTRODUCTION
Gestational Diabetes Mellitus (GDM) is defined as any degree of glucose intolerance which is diagnosed for the first time during pregnancy. This prospective study was undertaken to validate the single-step non-fasting 75-gm Diabetes in Pregnancy Study group of India (DIPSI) criteria of GDM in Indian patients in comparison with two-step fasting 100-gm glucose challenge through Carpenter-Coustan Criteria (CCC).
MATERIAL AND METHODS
200 patients underwent a comparative testing by DIPSI criteria and CCC. Plasma venous blood glucose levels were estimated by hexokinase method Values ≥140 mg/dl at 2-hours were considered positive by DIPSI criteria. Any two values from ≥95 mg/dl for fasting, ≥180 mg/dl at 1-hour, ≥155 mg/dl at 2-hours ≥140 mg/dl at 3-hours were considered positive by CCC.
RESULTS
Mean age and BMI were 24.26 ± 3.75 years and 20.7 ± 3.07 Kg/m2. The sensitivity, specificity, positive and negative predictive values of DIPSI guidelines was found to be 100%, 97.14%, 83.87% and 100% respectively. The positive and negative likelihood ratios were 35.8 and zero. Diagnostic accuracy was found to be 97.56%.
CONCLUSION
DIPSI having high sensitivity, specificity, negative predictive value and diagnostic accuracy. DIPSI offers simplicity, feasibility, convenience and repeatability while economizing universal screening and diagnosis of GDM on a mass-scale. DIPSI procedure has the potential to be applied to the entire obstetric population, in the implementation of public-health programs to diagnose GDM in the community, thus reaching the felt needs in the developing world.