Chorangiosis placenta with 5-vessel umbilical cord with omphalomesentric duct remnant: An unusual association

Placenta is an organ which is responsible for nourishing and protecting the fetus during pregnancy. Histological examination of placenta can yield significant information about pre-uterine and uterine conditions affecting fetal growth. Chorangiosis is defined as the presence of ≥10 terminal villi, each containing ≥10 capillaries per terminal villus in ≥10 low power (10×) fields in at least 3 or more random, non-infarcted cotyledons of placenta. Chorangiosis is an adaptive response to in-utero hypoxia and its presence signifies better pregnancy outcomes. Abnormalities which lead to multiple vessels in cord are rare with majority of the reported cases highlighting four vessels due to a persistent right umbilical vein. We report here a case of chorangiosis of placenta associated with the rare 5-vessel umbilical cord and omphalomesentric duct remnant. To the best of our knowledge, this is the first case documenting such an association.