. 2022; 39(1): 61-65 | DOI: 10.4274/tjh.galenos.2021.2021.0434 | |||
Pre-transplant Anjiyopoietin-2 İndeksinin Hematopoietik Kök Hücre Transplantasyonu Sonrası Akut Graft Versus Host Hastalığı Riski ile İlişkisiÖzlem Satırer1, Inci Cevher Zeytin2, Berna Alkan Mumcu2, Jale Karakaya4, Duygu Çetinkaya3, Fatma Visal Okur31Hacettepe University Faculty of Medicine, Department of Pediatrics, Ankara, Turkey2Hacettepe University, Center for Stem Cell Research and Development (PEDI-STEM), Ankara, Turkey 3Hacettepe University, Center for Stem Cell Research and Development (PEDI-STEM), Ankara, Turkey; Hacettepe University Faculty of Medicine, Department of Pediatrics, Division of Pediatric Hematology and Bone Marrow Transplantation Unit, Ankara, Turkey 4Hacettepe University Faculty of Medicine, Department of Biostatistics, Ankara, Turkey Amaç: Endotelyal stres altında salınan anjiyojenik faktörler (AF), doku iyileşmesini yansıtırken, bazıları doku hasarına/iltihabına katkıda bulunabilir. Bu çalışmamızda pre-transplant AF düzeylerindeki değişikliklerin akut graft versus host hastalığı (aGvHH) riski ile ilişkili olup olmadığını araştırdık. Association of Pre-Transplant Angiopoietin-2 Index with the Risk of Acute Graft-Versus-Host Disease after Hematopoietic Stem Cell TransplantationÖzlem Satırer1, Inci Cevher Zeytin2, Berna Alkan Mumcu2, Jale Karakaya4, Duygu Çetinkaya3, Fatma Visal Okur31Hacettepe University Faculty of Medicine, Department of Pediatrics, Ankara, Turkey2Hacettepe University, Center for Stem Cell Research and Development (PEDI-STEM), Ankara, Turkey 3Hacettepe University, Center for Stem Cell Research and Development (PEDI-STEM), Ankara, Turkey; Hacettepe University Faculty of Medicine, Department of Pediatrics, Division of Pediatric Hematology and Bone Marrow Transplantation Unit, Ankara, Turkey 4Hacettepe University Faculty of Medicine, Department of Biostatistics, Ankara, Turkey Objective: Angiogenic factors (AFs) released under endothelial stress are reflective of tissue healing, while some may also contribute to tissue damage/inflammation. We investigated whether alterations in the pre-transplant levels of AFs were associated with the risk of acute graft-versus-host disease (aGvHD). Özlem Satırer, Inci Cevher Zeytin, Berna Alkan Mumcu, Jale Karakaya, Duygu Çetinkaya, Fatma Visal Okur. Association of Pre-Transplant Angiopoietin-2 Index with the Risk of Acute Graft-Versus-Host Disease after Hematopoietic Stem Cell Transplantation. . 2022; 39(1): 61-65 Sorumlu Yazar: Fatma Visal Okur, Türkiye |
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