. 2017; 34(1): 93-98 | DOI: 10.4274/tjh.2015.0073 | |||
Ankaferd Hemostat’ın (ABS) Shiga Toksijenik Escherichia coli ve Diğer Gıda Patojenleri Üzerine Antibakteriyel EtkisiAhmet Koluman1, Nejat Akar2, İbrahim C. Haznedaroğlu31Republic of Turkey Ministry of Food, National Food Reference Laboratory, Department of Mineral Analyses, Agriculture, and Livestock, Ankara, Turkey2TOBB-ETU Hospital, Clinic of Pediatric Hematology, Ankara, Turkey 3Hacettepe University Faculty of Medicine, Department of Adult Hematology, Ankara, Turkey Amaç: Ankaferd hemostat (Ankaferd Blood Stopper®, ABS) gamma fibrinojene etki ederek eritroid agregasyonuna neden olan farmakolojik modülasyondur. Topikal endoskopik ABS uygulaması gastrointestinal (Gİ) kanamalarda ve enfekte Gİ yaralarında etkili olmaktadır. Escherichia coli O157: H7, en sık karşılaşılan enterohemorajik Escherichia coli tipi olup sporadik veya salgınlar şeklinde hemorajik kolitin önemli bir etkenidir. Bu çalışmanın amacı ABS ile 6 farklı Shiga Toksijenik Escherichia coli serotipi (O26, O103, O104, O111, O145 ve O157) ve diğer önemli gıda kaynaklı patojenlerden Salmonella, Campylobacter ve Listeria monocytogenes üzerine etkisi değerlendirilmiştir. Antibacterial Activities of Ankaferd Hemostat (ABS) on Shiga Toxin-Producing Escherichia coli and Other Pathogens Significant in Foodborne DiseasesAhmet Koluman1, Nejat Akar2, İbrahim C. Haznedaroğlu31Republic of Turkey Ministry of Food, National Food Reference Laboratory, Department of Mineral Analyses, Agriculture, and Livestock, Ankara, Turkey2TOBB-ETU Hospital, Clinic of Pediatric Hematology, Ankara, Turkey 3Hacettepe University Faculty of Medicine, Department of Adult Hematology, Ankara, Turkey Objective: Ankaferd hemostat (Ankaferd Blood Stopper®, ABS)- induced pharmacological modulation of essential erythroid proteins can cause vital erythroid aggregation via acting on fibrinogen gamma. Topical endoscopic ABS application is effective in the controlling of gastrointestinal (GI) system hemorrhages and/or infected GI wounds. Escherichia coli O157: H7, the predominant serotype of enterohemorrhagic E. coli, is a cause of both outbreaks and sporadic cases of hemorrhagic colitis. The aim of this study is to examine the effects of ABS on 6 different Shiga toxigenic E. coli serotypes including O26, O103, O104, O111, O145, and O157 and on other pathogens significant in foodborne diseases, such as Salmonella Typhimurium, Campylobacter jejuni, and Listeria monocytogenes, were also assessed. Ahmet Koluman, Nejat Akar, İbrahim C. Haznedaroğlu. Antibacterial Activities of Ankaferd Hemostat (ABS) on Shiga Toxin-Producing Escherichia coli and Other Pathogens Significant in Foodborne Diseases. . 2017; 34(1): 93-98 Sorumlu Yazar: Ahmet Koluman, Türkiye |
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