. 2015; 32(3): 206-212 | DOI: 10.4274/Tjh.2014.0058 | |||
Bortezomib and Arsenic Trioxide Activity on a Myelodysplastic Cell Line (P39): A Gene Expression StudyHakan Savlı1, Sara Galimberti2, Deniz Sünnetçi1, Martina Canesastraro2, Giuseppe Palumbo3, Balint Nagy4, Francesco Di Raimondo3, Mario Petrini21Kocaeli University Faculty of Medicine, Department of Medical Genetics, Kocaeli, Turkey2Pisa University Faculty of Medicine, Department of Clinical and Experimental Medicine, Division of Hematology, Pisa, Italy 3Catania University Faculty of Medicine, Department of Clinical and Molecular Bio-Medicine, Division of Hematology, Catania, Italy 4Semmelweis University Faculty of Medicine, Department of Obstetrics and Gynecology, Budapest, Hungary INTRODUCTION: We aimed to understand the molecular pathways affected by bortezomib and arsenic trioxide treatment on myelomonocytoid cell line P39. Bir Miyelodisplastik Hücre Hattı (P39) Üzerine Bortezomib ve Arsenik Trioksid’in Etkileri: Bir Gen Anlatımı ÇalışmasıHakan Savlı1, Sara Galimberti2, Deniz Sünnetçi1, Martina Canesastraro2, Giuseppe Palumbo3, Balint Nagy4, Francesco Di Raimondo3, Mario Petrini21Kocaeli University Faculty of Medicine, Department of Medical Genetics, Kocaeli, Turkey2Pisa University Faculty of Medicine, Department of Clinical and Experimental Medicine, Division of Hematology, Pisa, Italy 3Catania University Faculty of Medicine, Department of Clinical and Molecular Bio-Medicine, Division of Hematology, Catania, Italy 4Semmelweis University Faculty of Medicine, Department of Obstetrics and Gynecology, Budapest, Hungary GİRİŞ ve AMAÇ: Bu çalışmada, bir myelomonositoid hücre hattı olan P39 üzerinde bortezomib ve arsenik trioksidin etkilediği moleküler altyolları anlamayı amaçladık. Hakan Savlı, Sara Galimberti, Deniz Sünnetçi, Martina Canesastraro, Giuseppe Palumbo, Balint Nagy, Francesco Di Raimondo, Mario Petrini. Bortezomib and Arsenic Trioxide Activity on a Myelodysplastic Cell Line (P39): A Gene Expression Study. . 2015; 32(3): 206-212 Corresponding Author: Deniz Sünnetçi, Türkiye |
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