. 9999; 0: 0-0

Evaluation of Serum 25-oh Vitamin D, Vitamin B12 and Folate Levels in Benign Paroxysmal Positional Vertigo Patients

Hamit Çelik1, AHMET YARDIM2, Atilla Ertaş3, Behçet Varışlı4, Özgül Ocak5
1Private Buhara Hospital Department of Neurology, Erzurum, Turkey
2Private Buhara Hospital Neurosurgery Clinic, Erzurum, Turkey
3Private Buhara Hospital Otolaryngology Clinic, Erzurum, Turkey
4Canakkale State Hospital Emergency Department Clinic, Çanakkale, Turkey
5Çanakkale Onsekiz Mart University Faculty of Medicine Department of Neurology, Çanakkale, Turkey

Aim: To compare 25-hydroxyvitamin D (25-OH Vit D),Vitamin B12,and folic acid levels of patients presenting with vertigo and who were diagnosed with Benign Paroxysmal Positional Vertigo (BPPV) and of the healthy volunteer control group without vertigo and to examine whether they are associated with the disease.

Materials and Methods: 190 patients who applied to between October-December 2019 and who were diagnosed with BPPV,and 49 volunteers without any complaints (control group) who came only for check-up were included in the study. Serum 25-OH Vit D,Vitamin B12, and folic acid levels of all participants were examined.

Results: Of the participants,209(61.6%)were male and 130(38.4%)were female.Of 94 participants included in the study,25-OH Vit D level was found to be at low levels. Of the participants with low 25-OH Vit D levels,65 (69.1%)were in the BPPV group and 29(30.9%) were in the control group. Of all participants included in the study, 68 had low folic acid levels and 33 (48.5%)of them were in the control group, while 35 (51.5%) of them were in the BPPV group.The level of Vitamin B12 of 2 participants among all participants included in the study was below the normal values and these 2 participants were in the BPPV group.

Conclusion: In our study,we did not found any significant relationship between BPPV and serum Vitamin B12 and serum folic acid levels.We determined a significant relationship between BPPV and decreased serum 25-OH Vit D level (p<0.01). We identified that low serum 25-OH Vit D levels may be an independent risk factor in the progress of BPPV.

Keywords: Vertigo, Benign Paroxysmal Positional Vertigo, 25- OH Vitamin D, Vitamin B12, Folic Acid


Hamit Çelik, AHMET YARDIM, Atilla Ertaş, Behçet Varışlı, Özgül Ocak. Evaluation of Serum 25-oh Vitamin D, Vitamin B12 and Folate Levels in Benign Paroxysmal Positional Vertigo Patients. . 9999; 0: 0-0

Corresponding Author: Hamit Çelik, Türkiye


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