QTc, Tp-e Interval and Tp-e/QTc ratio Changes in Hypoxia due to Hypertansive Pulmonary Edema-Case Control Study

Objective: As far as we have investigated, although there are researches on QT and QTc interval, there are no studies evaluating T wave peak-to-end distance (Tp-e interval), the ratio of Tp-e to QT and QTc used in the evaluation of cardiac arrhythmia risk and ventricular repolarization changes in patients with hypoxia due to hypertensive pulmonary edema. Therefore, in this study was aimed to study whether there is a change in Tp-e interval, the ratio of Tp-e to QTc in hypoxia due to hypertensive pulmonary edema.
Methods: Forty patients diagnosed with hypertensive pulmonary edema in the emergency room were included in the study retrospectively. Forty patients with similar age and gender distribution were included in the study as a control group. All patients underwent 12-lead electrocardiography (ECG). In addition to the routine measurements, Tp-e interval, the ratio of Tp-e to QTc were measured in ECG. Study data were grouped as patients with and without hypoxia
Results: Mean age for patients was 68.60 ± 15.25. QTc interval, Tp-e interval and Tpe / QTc values were found to be significantly higher in hypoxia caused by hypertensive pulmonary edema (p <0.001 for each). QTc interval, Tp-e interval and Tpe / QTc ratio showed significant negative correlation with hypoxia levels.
Conclusion: In patients with hypertensive pulmonary edema, Tp-e interval and Tp-e/QTc rates are increased significantly compared to those without hypertensive pulmonary edema, and these measurements can be used more effectively in the close follow-up of cardiac fatal arrhythmias.