Evaluation of the relationship between CRP, Lactate, Procalcitonin and Albumin levels with SOFA and APACHE-II in Emergency ICU patients

Aim: This study was to investigate the efficacy of procalcitonin, CRP, lactate, albumin and procalcitonin / albumin parameters used as an indicator of infection on mortality in critical patients admitted to the Intensive Care Unit and their relationship with APACHE II, SOFA scores.
Materyal-Methods: The study was carried out from hospital records of patients and scans of patient files.Demographic characteristics, procalcitonin, CRP, albumin and lactate levels as well as APACHE-II and SOFA scores were recorded. Spearman's rank correlation was used for non-parametric data. ROC curve analysis was performed to determine the threshold value of blood parameters. Results: 61 patients were enrolled into the present study. The participants included 35 males (57.4%) and 26 females (42.6%) with an age average of 69.0. A positive and weakly significant association was detected between APACHE-II and procalcitonin.When the APACHE-II Score and lactate and procalcitonin / albumin ratio were evaluated; APACHE-II was positively significant and had a weak correlation with lactate and procalcitonin / albumin ratio. A moderate negative correlation was found between albumin and APACHE-II score.The SOFA score was positively associated with procalcitonin.The SOFA score was positively associated lactate. SOFA was positively significant and weakly correlated with Procalcitonin / Albumin ratio.
Conclusion: Procalcitonin, lactate, albumin and procalcitonin / albumin were considered as prognostic markers according to the cut-off points in terms of mortality in critically ill patients.In addition, these blood parameters were found to be useful in clinical follow-up as they were related to the APACHE-II and SOFA scoring systems used in intensive care units.