. 9999; 0: 0-0

the effect of blood glucose value on the short-term mortality of acute ischemic stroke

Serhat Tokgoz1, Feridun Karakurt2, ahmet BUGRUL1
1Department of Neurology, Necmettin Erbakan University, Meram Medical Faculty, Konya, Turkey
2Department of Endocrinology, Necmettin Erbakan University, Meram Medical Faculty, Konya, Turkey

Aim: It is aimed to examine the relationship between short-term mortality and the blood glucose values (BGV) obtained in the first week of ischemic stroke, when neurological causes such as increased intracranial pressure are mainly predominant in mortality.
Materials and Methods: This is a retrospective study of 417 patients with acute ischemic stroke (AIS) who admitted to our hospital within the first 24 hours. Data were recorded using the International Classification of Diseases Code. The effect of BGV on the first, third, fifth and seventh day of the stroke on the patient’s functional outcome was evaluated.
Results: Of 417 patients, 90 (21.58%) died within a one-month follow-up period. There was no difference between the mortality and survival groups in terms of diabetes mellitus history (χ2 = 0.783, p: 0.224). BGV’s were significantly higher in the mortality group than in the others at 1st, 3rd, 5th, and 7th days (p <0.05). Blood glucose predictive values on these days for mortality were found 130.5; 124.5; 133.5; 132.5 mg / dL respectively, in the Receiver Operating Characteristic (ROC) analysis. The 5th day BGV (133.5 mg/dL) was an independent predictor for mortality (HR: 3.001; 95% CI (1.43 - 6.3) p: 0.004), while the others were dependent to coma scale.
Conclusion: Hyperglycemia predicting short-term-AIS mortality might be a DM-independent stress hyperglycemia. Although hyperglycemia is predominantly a coma scale dependent (mRS) predictor at first-week-blood glucose monitoring, the fifth day blood glucose value may be independent predictor of short-term mortality.

Keywords: Glucose, Stroke, Mortality, Outcome


Serhat Tokgoz, Feridun Karakurt, ahmet BUGRUL. the effect of blood glucose value on the short-term mortality of acute ischemic stroke. . 9999; 0: 0-0

Corresponding Author: Serhat Tokgoz, Türkiye


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