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1.E-Pharmacophore Mapping Combined with Virtual Screening and Molecular Docking to Identify Potent and Selective Inhibitors of P90 Ribosomal S6 Kinase (RSK)
Abdulilah Ece

Abstract

2.A Review On: Phase “0” Clinical Trials Or Exploratory Investigational New Drug
Ashish A. Gawai, Faisal Shaikh, Mangesh Gadekar, Nitin Deokar, Shivanand Kolhe, K. R. Biyani

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3.Anatomical Studies on Verbascum pestalozzae Boiss. and Verbascum pycnostachyum Boiss. & Heldr.
Sevim Küçük, Melike Belkıs Gökçe, Ramazan Süleyman Göktürk

Abstract

4.Antimicrobial Activities of New Indole Derivatives Containing 1,2,4-Triazole, 1,3,4-Thiadiazole and Carbothioamide
Hanif Shirinzadeh, Sibel Suzen, Nurten Altanlar, Andrew D.westwell

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5.Bio fabrication of Copper Nanoparticles: A Next Generation Antibacterial Agent against Wound Associated Pathogens
Pallavi Singh Chauhan, Vikas Shrivastava, Rajesh Singh Tomar

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6.Biopharmaceutical Process of Diclofenac Multiparticulate Systems for Chronotherapy of Rheumatoid Arthritis
Sowjanya Battu, Prasanna Raju Yalavarthi, Subba Reddy GV, Saradha Radhakrishnan, Ram Mohan Reddy Thummaluru, Abbulu Konde

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7.Comparative Characteristics of Antidepressant, Anti-Hypoxic Action and Effect on the Physical Endurance of Scutellaria baicalensis Drugs
Galina Slipchenko

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8.Design and Development of Crystallo-co-agglomerates of Ritonavir for the Improvement of Physicochemical properties.
Nilesh M Mahajan, Ashwini D Malghade, Nitin G Dumore, Raju R Thenge

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9.Design, Formulation and In-Vitro Evaluation of Sustained Release Tablet Formulations of Levosulpiride
Muhammad Samie, Sajid Bashir, Jabbar Abbas, Samiullah Khan, Nargis Aman, Habibullah Jan, Naveed Muhammad

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10.Design, synthesis and evaluation of biological activities of some new carbohydrazide and urea derivatives
Fatih Tok, Recep İlhan, Selin Günal, Petek Ballar-kırmızıbayrak, Bedia Koçyiğit-kaymakçıoğlu

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11.Development and full validation of a stability-indicating RP-LC method for the determination of anticancer drug Temozolomide in pharmaceutical form
Evin Kapçak, Eda Hayriye Şatana Kara

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12.Development of the composition and manufacturing technology of the new combined drug Lavaflam
Tanya Ivko, Milena Aslanian, Larisa Bobrytska, Natalia Popova, Olena Nazarova, Natalia Bereznyakova, Tamara Germanyuk

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13.Formulation and Evaluation of Sintered Floating Tablets of Cefpodoxime Proxetil
Latha Kukati, Kishore Chittimalli, Naseeb Basha Shaik, Shailaja Thoudoju

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14.Formulation and optimization of gentamicin hydrogel infused with tetracarpidium conophorum extract via Central composite design for topical delivery
Margaret Okonawan Ilomuanya, Nosakhare Andrew Amenaghawon, Joy Odimegwu, Omotunde Olufunke Okubanjo, Chinelo Aghaizu, Adeyinka Oluwatobiloba, Thomas Akimien, Tolulope Ajayi

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15.Glucose lowering effect of Zornia gibbosa Span extracts in diabetic rats
Mallikarjuna Rao Talluri, Rajananda Swamy Tadi, Ganga Rao Battu, Zubair Mohammad

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16.Investigation of antimicrobial activities of some herbs containing essential oils and their mouthwash formulations
Büşra Kulaksız, Sevda Er, Neslihan Üstündağ Okur, Gülçin Saltan İşcan

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17.Levels of Heavy Metals and Ochratoxin A in Medicinal Plants Commercialized in Turkey
Hakan Özden, Sibel Özden

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18.Oxidative stress and anti-oxidants in pre and post operative cases of breast carcinoma
Sohail Hussain, Mohammad Ashafaq

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19.Phytotoxicity, Toxicity on Brine Shrimp and Insecticidal Effect of Chrysophthalmum gueneri Aytac & Anderb. Growing in Turkey
Fatma Ayaz, Nurgün Küçükboyacı, Barış Bani, Bilge Şener, Muhammad Iqbal Choudhary

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20.Simultaneous determination of arbutin and hydroquinone in different herbal slimming products by Gas Chromatography-Mass Spectrometry
Benan Dursunoğlu, Hafize Yuca, Zühal Güvenalp, Sefa Gözcü, Bilal Yılmaz

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21.Structure Elucidation and Antimicrobial Activities of Secondary Metabolites From The Flowery Parts of Verbascum mucronatum Lam.
Çiğdem KAHRAMAN, İffet İrem TATLI, Didem KART, Melike EKİZOĞLU, Zeliha Şükran AKDEMİR

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22.Synthesis and Evaluation of A New Series of Thiazolyl-Pyrazoline Derivatives as Cholinesterase Inhibitors
Halide Edip Temel, Mehlika Dilek Altıntop, Ahmet Özdemir

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23.The Apoptotic and Anti-Apoptotic Effects of Pendimethalin and Trifluralin on A549 Cells In Vitro
Zehra Sarıgöl Kılıç, Ülkü Ündeğer Bucurgat

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24.The effect of sumatriptan in ischemic conditions in the rat heart
Hande Özge Altunkaynak Çamca, Müge Tecder Ünal, Meral Tuncer

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25.A Validated RP-UPLC Method for the Determination of Gemifloxacin Mesylate in Bulk and its Pharmaceutical Preparation.
Hebatallah A Wagdy, Mohamed Tarek, Ahmed Amer, Menna Gamal, Mohey Elmazar

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26.Antiplasmodial activity of the n-hexane extract from Pleurotus ostreatus (Jacq. Ex. Fr) P. Kumm.
Ozadheoghene Eriarie Afieroho, Xavier Siwe Noundou, Chiazor P Onyia, Osamuyi H Festus, Elizabeth C Chukwu, Olutayo M Adedokun, Michelle Isaacs, Heinrich C Hoppe, Rui WM Krause, Kio A Abo

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27.Characterization of gamma-irradiated Rosmarinus officinalis L. (Rosemary)
Marzieh Heidarieh, Reza Rezanejad, Seyed Mahdi Ojagh, Mojtaba Raeisi, Gholamreza Rafiee, Alireza Alishahi

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28.Comparison of Essential Oils of Ferula orientalis L., Ferulago sandrasica Peșmen & Quézel and Hippomarathrum microcarpum Petrov and Their Antimicrobial Activity
Songül Karakaya, Gamze Göger, Fatmagül D. Bostanlık, Betül Demirci, Hayri Duman, Ceyda Sibel Kılıç

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29.Degradation kinetics, in-vitro dissolution studies and quantification of praziquantel anchored in emission intensity by spectrofluorimetry
Panikumar Durga Anumolu, Sunitha Gurrala, Ceema Mathew, Vasavi Panchakatla, Veda Maddala

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30.Determination Of Potential Drug-Drug Interactions By Using Various Software Programs At Community Pharmacy Setting
Mesut Sancar, Aksa Kaşık, Betul Okuyan, Sevda Batuhan, Fikret Vehbi İzzettin

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31.Development of discriminative and biorelevant dissolution test method for atorvastatin /fenofibrate combination with appliance of derivative spectrophotometry.
Panukumar Durga Anumolu, Sunitha Gurrala, Subrahmanyam Chavali Venkata Satya, Santoshi Vani Polisetty, Anjana Ravindran, Radhagayathri Achanta

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32.Effect of lipid peroxidation product 4-hydroxynonenal on neuroinflammation in microglial cells: Protective role of Quercetin and Monochloropivaloylquercetin
Ahmet Cumaoğlu, Aslı Özge Ağkaya, Zehra Özkul

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33.Enhancement of Dissolution of Fenofibrate using complexation with Hydroxy propyl β – Cyclodextrin
Sachin K Jagdale, Mohammad H Dehghan, Nilesh S Paul

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34.Establishment and Escalation of Amino Acid Stacked Repressible Release Embedded System Using QbD
Vijay Sharma, Lalit Singh, Navneet Verma

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35.Is There an Association Between Extreme Level of Boron Exposure and Decrease in Y: X Sperm Ratio in Men? Results of an Epidemiological Study
Can Özgür Yalçın, Aylin Üstündağ, Yalçın Duydu

Abstract

36.Microanatomical, Physicochemical characterization, and antioxidative activity of methanolic extract of Oudemansiella canarii (Jungh.) Höhn
Krishnendu Acharya, Sudeshna Nandi, Arun Kumar Dutta

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37.Preclinical evaluation of haematinic activity of oral indiffusible mixture of Tamarindus indica L. leaf extract
Sathiya Ramu, Shwetha Krishna Murthy, Sukanya Krishna, Abhishek Lakkasandra Somashekaraiah, Vani B Nandihalli, Kanekal Mohammed Muzammil

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38.Quantification of Galantamine in Sterbergia Species by High Performance Liquid Chromatography
Özlem Bahadır Acıkara, Betül Sever Yılmaz, Dilhun Yazgan, Gülçin Saltan İşcan

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39.Sub-chronic toxicity assessment of orally administered methanol (70%) seed extract of Abrus precatorius L. in Wistar albino rats
Shazia Tabasum, Swati Khare, Kirti Jain

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40.Synthesis and aldose reductase inhibitory effect of some new hydrazinecarbothioamides and 4-thiazolidinones bearing imidazo[2,1-b]thiazole moiety
Nuray Ulusoy Güzeldemirci, Selin Cimok, Net Daş-Evcimen, Mutlu Sarıkaya

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41.A Comprehensive Study on Thiadiazole-Based Anticancer Agents Inducing Cell Cycle Arrest and Apoptosis/Necrosis through Suppression of Akt Activity in Lung Adenocarcinoma and Glioma Cells
Gülşen Akalın Çiftçi, Belgin Sever, Mehlika Dilek Altıntop

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42.Antimicrobial and Anti-Inflammatory Activity of Some Lathyrus L. (Fabaceae) Species Growing In Turkey
Hajar Heydari, Gülçin Saltan İşcan, Müjde Eryılmaz, Özlem Bahadır Acıkara, Sezen Yılmaz Sarıaltın, Mehmet Tekin, Tülay Çoban

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43.Decreased Protein Kinase C expressions in the cochlear fibroblasts of diabetic rat models induced by curcumin
Tengku Siti Hajar Haryuna, Farhat Farhat, Siska Indriany

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44.Electroanalytical Determination of Antiinflammatory Drug Tenoxicam in Pharmaceutical Dosage Forms
Fatma Ağın, Sena Atal

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45.Essential Oil and Fatty Acid Composition of Endemic Gypsophila laricina Schreb. from Turkey
Hüseyin Servi, Betül Eren Keskin, Sezgin Çelik, Ümit Budak, Büşra Kababıyık

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46.Flavonoid Glycosides From Heracleum pastinaca Fenzl.
Perihan Gürbüz

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47.Identification, Quantification and Antioxidant Activity of Hydro-alcoholic Extract of Artemisia campestris from Algeria
Bakchiche Boulanouar B.bakchiche@lagh Univdz, Gherib Abdelaziz A.gherib@mail.lagh-univ.dz, Ghareeb Mosad A. B.bakchiche@mail.lagh-univ.dz, Bronze Maria Rosário Bakchicheboulanouar@gmail.com

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48.Investigation of antioxidant, α-glucosidase inhibitory, anti-inflammatory and DNA protective properties of Vaccinium arctostaphylos L.
Burak Barut, Elif Nur Barut, Seçkin Engin, Arzu Özel, Feride Sena Sezen

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49.Investigation of Polyphenol Composition, Biological Activities and Detoxification Properties of Some Medicinal Mushrooms from Turkey
Naznoosh Shomali, Okan Onar, Tuğçe Alkan, Nergiz Demirtaş, Ilgaz Akata, Özlem Yıldırım

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50.Optimization of Immobilized Aldose Reductase Isolated from Bovine Liver
Marya Vakıl Naslıyan, Sidar Bereketoğlu, Özlem Yıldırım

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51.Optimization Of Thiazolidone Scaffolds Using Pocket Modelling For Development Of Potential Secretary System Inhibitors of Mycobacterium Tuberculosis
Prafulla Balkrishna Choudhari, Shivaratna V Khare, Siddharth P Phalle, Santosh S Kumbhar, Sambhaji Masal, Rakesh P Dhavale, Durgacharan A Bhagwat, Atual M Kadam, Sujata P Choudahri

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52.Preparation and Biopharmaceutical Evaluation of Novel Polymeric Nanoparticles Containing Etoposide for targeting the cancer cells
Ayyappan Thiyagarajan

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53.Quantitative Structure–Activity Relationship Analysis of Selective Rho Kinase Inhibitors as Neuro-regenerator agent
Seema Kesar, Sarvesh K Paliwal, Pooja Mishra, Monika Chauhan

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54.Screening of Sacrificial Excipients for Arresting Devitrification of Itraconazole from Solid Dispersion
Bhargavi M. Patel, Mukesh C. Gohel, Vaishali T. Thakkar, Lalji H. Baldaniya, Ruby R. Christian, Tejal R. Gandhi

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55.Simultaneous estimation of saxagliptin and dapagliflozin in human plasma by validated HPLC-UV method
Sharmila Donepudi, Suneetha Achanta

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56.Study of the tableting properties of MCR, a newly co-processed cellulose based direct compression excipient
Salah Aly

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57.An in vitro study on the cytotoxicity and genotoxicity of silver sulphide quantum dots coated with meso-2,3-dimercaptosuccinic acid
Deniz Ozkan Vardar, Sevtap Aydin, İbrahim Hocaoglu, Havva Yagci Acar, Nursen Basaran

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58.Anti-Angiogenic activity of flunarizine by in ovo, in vitro and in vivo assays.
Chandana Kamili, Ravi Shankar Kakaraparthy, Uma Maheshwararao Vattikuti

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59.Anti-cancer and anti-inflamatory effects of Centaurea solstitialis extract on human cancer cell lines
Mehlika Alper, Hatice Güneş

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60.Design and in vitro evaluation of Eudragit-based extended release diltiazem microspheres for once and twice daily administrations: the effect of coating on drug release behavior
Noushin Bolourchian, Maryam Bahjat

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61.Development and Optimization of Floating Multiparticulate Drug Delivery System of Norfloxacin
Rakesh Kumar Mishra, Tanaji Dilip Nandgude, Vaibhav Shivajirao Salve

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62.Effect of Aerial Parts and Root Extracts from Four Ferulago Species on Erectile Dysfunction in Streptozotocin-Induced Diabetic Rats
Songül Karakaya, Didem Yılmaz Oral, Serap Gur, Hayri Duman, Ceyda Sibel Kılıc

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63.Evaluation of Alchemilla persica Rothm. antidiabetic activity on mice induced by alloxan
Serkan Özbilgin, Hanefi Özbek, Neriman İpek Kırmızı, Burçin Ergene Öz, Ekin Kurtul, Bade Cevriye Özrenk, Gülçin Saltan İşcan, Özlem Bahadır Acıkara

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64.Ficus species good sources of natural antioxidant drugs
Parul Akhtar, Zahira Yaakob, Yunus Ahmed, Md. Shahinuzzaman

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65.Formulation Design of Hydrocortisone Films for The Treatment of Aphthous Ulcer
Mohammed Gulzar Ahmed Mohammed, Sanjana Adinarayana Adinarayana

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66.Histone Deacetylase Inhibitors: A Prospective In Drug Discovery
Rakesh Yadav, Pooja Mishra, Divya Yadav

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67.In Vitro Macrophage Nitric Oxide and Interleukin-1 Beta Suppression by Moringa Peregrina Seed
Shaymaa Fadhel Abbas Albaayit, Ahmed Salim Kadhim Al-Khafaji, Hiba Sarmed Alnaimy

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68.Investigation of gelatinase gene expression and growth of E. faecalis clinical isolates in biofilm models
Didem Kart, Ayşe Semra Kuştimur

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69.Palmitic Acid-Pluronic F127-Palmitic Acid Penta-Block Copolymer as a Novel Nanocarrier for Oral Delivery of Glipizide
Vipan Kumar Kamboj, Prabhakar Kumar Verma

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70.Phytochemical screening, metallic ion content and from its impact on Anti psoriasis activity of Calendula officinalis and Phlebodium decumanum aqueous leaf extracts in animal experiment model
Kuntal Das, Someswar Deb, Tejaswini Karanth

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71.Superior solubility and dissolution of zaltoprofen via pharmaceutical cocrystal
Prabhakar Panzade, Giridhar Shendarkar

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72.Synthesis and swelling behavior of sodium alginate / poly (vinyl alcohol) hydrogels
Demappa Thippaiah, Shivakumara Lachakkal Rudrappa

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73.The influence of piperine on radioprotective effect of curcumin in irradiated human lymphocytes
Seyed Jalal Hosseinimehr, Nora Gheleshli, Arash Ghasemi

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74.A rapid stability indicating HPLC method for the analysis of Leflunomide and its related impurities in bulk drug and formulations
Useni Reddy Mallu, Venkateswara Rao Anna, Bikshal Babu Kasimala

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75.Antibacterial and antibiofilm activities of ceragenins against Pseudomonas aeruginosa clinical isolates
Çağla Bozkurt Güzel, Mayram Hacıoğlu, Gözde İnci, Paul B Savage

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76.Antifungal activity of silver nanoparticles in a murine model of oral candidiasis
Chukwunonso Ecc Ejike, Abdulrazzaq A. Almaweri, Adel Al-marby, Sawsan A. Zaitone, Essam A Al-moraissi, Marwa M Azab, Abdel-nasser M. Al Refai, Salah M. Abdalla, Magda M. Hassan, Pierre A Hannah

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77.Comparative in vitro assessment of the methanol extracts of the leaf, stem and root barks of Cnidoscolus aconitifolius on lung and breast cancer cell lines
Emmanuel Oise Ikpefan, Buniyamin Adesina Ayinde, Mudassir Azhar, Farooq Ahsana Dar

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78.Considering the effect of Rosa Damascena essential oil on oxidative stress and COX-2 gene expression in liver of septic rats
Abolfazl Dadkhah, Faezeh Fatemi, Mohammad Reza Mohammadi Malayeri, Mohammad Hassan Karvin Ashtiyani, Sakineh Kazemi Noureini, Azadeh Rasooli

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79.Cytotoxic activity of daucane sesquiterpene esters isolated from endemic Ferula tenuissima HUB. MOR & PEŞMEN
Fadime Aydoğan, Şura Baykan, Bilge Debeleç Bütüner

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80.Effect of surfactant on azithromycin dihydrate loaded stearic acid solid lipid nanoparticles
Sayani Bhattacharyya, Priyanka Reddy

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81.Flavonoids Isolated from Vitex grandifolia: An Underutilized Vegetable, Exert Monoamine A & B Inhibitory and Anti-Inflammatory Effects and Structure Activity Relationship (SAR)
Oluwasesan M Bello, Abiodun B. Ogbesejana, Charles Oluwaseun Adetunji, Stephen O Oguntoye

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82.Impact of particle-size reduction on solubility and antidiabetic activity of extracts of leaves of Vinca rosea
Khalid Hussain, Abida Qamar, Nadeem Irfan Bukhari, Amjad Hussain, Naureen Shehzadi, Shaista Qamar, Sajida Parveen

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83.In vitro Evaluation of Chemical Composition and Various Biological Activities of Ficus carica Leaves Extracts
Mustafa Ergül, Merve Ergül, Nuraniye Eruygur, Mehmet Ataş, Esra Uçar

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84.Intrinsic Stability Study and Forced Degradation Profiling of Olopatadine hydrochloride by RP-HPLC-DAD-HRMS Method
Pawan Kumar Basniwal, Deepti Jain

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85.Investigation of the Voltammetric Behavior of Methyldopa at Poly (p-Aminobenzene Sulfonic Acid) Modified Sensor
Gamze Erdoğdu, Şevket Zişan Yağcı, Ebru Kuyumcu Savan

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86.Phytochemical screening and toxicological evaluation of sargassum wightii greville in wistar rats
Sathiya Ramu, Anita Murali, Anbu Jayaraman

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87.Phytotherapy for multiple sclerosis: A review
Zahra Rabiei

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88.Some New Hydrazone Derivatives Bearing 1,2,4-Triazole Moiety As Potential Antimycobacterial Agents
Keriman Özadalı Sarı, Oya Ünsal Tan, Dharmarajan Sriram, Ayla Balkan

Abstract

89.Spectrophotometric Quantification of Anti-Inflammatory Drugs by Application of Chromogenic Reagents
Panukumar Durga Anumolu, Sunitha Gurrala, Archana Gellaboina, Divya Gayathri Mangipudi, Sahitya Menkana, Rajesh Chakka

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90.Synthesis, Hypoglycemic, Anti-inflammatory Activity Screening of Novel Substituted 5-[morpholino(phenyl)methyl]-thiazolidine-2,4-diones and Their Molecular Docking Studies
Srikanth Kumar Karumanchi, Lakshmana Rao Atmakuri, V Basaveswara Rao Mandava, Srikala Rajala

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91.An in vitro study on the interactions of pycnogenol® with cisplatin in human cervical cells
Merve Becit, Sevtap Aydin

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92.Deposition Pattern of Polydisperse Dry Powders in Andersen Cascade Impactor – Aerodynamic Assessment for Inhalation Experimentally and in Silico
Janwit Dechraksa, Tan Suwandecha, Teerapol Srichana

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93.Formulation and characterization of etoricoxib solid dispersion using natural polymers
Sandip Babarao Sapkal, Vaibhav Suresh Adhao, Raju Rambhau Thenge, Rahul Ashok Darakhe, Sushilkumar Ananda Shinde, Vinayak Natthuji Shrikhande

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94.GC/MS Analysis of Alkaloids in Galanthus fosteri Baker and Determination of Its Anticholinesterase Activity
Ahmet Emir, Ceren Emir, Buket Bozkurt, Nehir Ünver Somer

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95.Levocetirizine Dihydrochloride Loaded Chitosan Nanoparticles: Formulation and In Vitro Evaluation
Gülsel Yurtdaş Kırımlıoğlu, Ahmet Alper Öztürk

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RESEARCH ARTICLE
96.Analysis of Drug Dosing Adjustments in Patients with Chronic Kidney Disease in Hospitals of Islamabad
Saeed Nazir, Amer Muhammad, Saleha Sadeeqa, Muhammad Kazim Zargaham, Sehran Saba, Muhammad Adnan Bashir, Saeed Ur Rashid Nazir

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97.Effects of glycyrrhetic acid on human chronic myelogenous leukemia cells
Halilibrahim Ciftci

Abstract

98.In vitro skin permeation and antifungal activity of naftifine microemulsions
Meryem Sedef Erdal, Aslı Gürbüz, Seher Birteksöz Tan, Sevgi Güngör, Yıldız Özsoy

Abstract

REVIEW
99.The contribution of serotonergic receptors and nitric oxide systems in the analgesic effect of acetaminophen: An overview of the last decade
Yeşim Hamurtekin, Ammar Nouilati, Cansu Demirbatır, Emre Hamurtekin

Abstract