Fournier’s gangrene: Five years’ experience from a single center in Turkey

BACKGROUND: Is the present study aims to analyze demographic, clinical and surgical data of all patients with FG (Fournier’s gangrene) admitted to a tertiary healthcare hospital in the largest city of Turkey.
METHODS: This study included 35 patients with Fournier’s gangrene, who were followed by the General Surgery, Plastic Surgery, and Urology Departments of Istanbul University Cerrahpaþa Faculty of Medicine from January 2010 to January 2015. Demographic and clinical data, including gender, age, length of stay at the hospital, the underlying cause(s), number of debridement, predisposing factors, and surgical reconstructive data over 10 years were assessed and analyzed retrospectively.
RESULTS: The mean age of the 35 patients was 58.14±12.71 years. Diabetes mellitus was present in 20 of the 35 (57.1%) patients. Twelve of the patients (34.2%) were hospitalized in the intensive care unit (ICU). Length of stay in the ICU was found to be significantly influenced by age, hematocrit level, FGSI and UFGSI (p=0.013, p=0.030 p=0.025 and p=0.002, respectively).
CONCLUSION: Fournier’s gangrene is a fulminant infection with a high mortality rate. Physical examination and anamnesis are quite important for the diagnosis of FG. DM is the most common comorbidity. Age, hematocrit level, FGSI and UFGSI scores affect the patients’ length of stay in the ICU.

Fournier gangreni: Türkiye’deki tek bir merkezden beþ yýllýk deneyimlerimiz

AMAÇ: Bu çalýþmanýn amacý, Ýstanbul’daki üçüncü basamak bir hastaneye baþvuran Fournier gangreni hastalarýnýn demografik, klinik ve cerrahi verilerini analiz etmektir.
GEREÇ VE YÖNTEM: Çalýþmaya Ocak 2010–Ocak 2015 tarihleri arasýnda Ýstanbul Üniversitesi-Cerrahpaþa Cerrahpaþa Týp Fakültesi Genel Cerrahi, Plastik Cerrahi ve Üroloji Anabilim Dallarý tarafýndan takip edilen Fournier gangrenli 35 hasta dahil edildi. Cinsiyet, yaþ, yatýþ süresi, altta yatan neden(ler), debridman sayýsý, predispozan faktörler ve 10 yýllýk bir süre içinde cerrahi ile ilgili veriler geriye dönük olarak deðerlendirildi ve analiz edildi.
BULGULAR: Otuz beþ hastanýn yaþ ortalamasý 58.14±12.71 idi. Otuz beþ hastanýn 20’sinde (%57.1) diabetes mellitus (DM) mevcuttu. Hastalarýn 12’si (%34.2) yoðun bakým ünitesinde (YBÜ) yatýrýldý. YBÜ’de kalma süresinin yaþ, hematokrit seviyesi, FGSI ve UFGSI’den anlamlý derecede etkilendiði bulundu (sýrasýyla, p=0.013, p=0.030 p=0.025 ve p=0.002).
TARTIÞMA: Fournier gangreni, mortalite oraný yüksek fulminan bir enfeksiyondur. FG tanýsý için fizik muayene ve öykü oldukça önemlidir. En sýk görülen komorbidite DM’dir. Yaþ, hematokrit seviyesi, FGSI ve UFGSI skorlarý hastalarýn YBÜ’de kalýþ sürelerini etkilediði bulunmuþtur.