ISSN 1016-5169 | E-ISSN 1308-4488
Archives of the Turkish Society of Cardiology
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A rare complication of chronic granulomatous disease in a child: constrictive aspergillus pericarditis [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2017; 45(7): 660-663 | DOI: 10.5543/tkda.2017.52284

A rare complication of chronic granulomatous disease in a child: constrictive aspergillus pericarditis

Emrah Şişli1, Yasemin Özdemir Şahan2, Mehmet Fatih Ayık1, Deniz Nart3, Yüksel Atay1
1Department of Cardiovascular Surgery, Ege University Faculty of Medicine, İzmir, Turkey
2Department of Pediatric Cardiology, Ege University Faculty of Medicine, İzmir, Turkey
3Department of Pathology, Ege University Faculty of Medicine, İzmir, Turkey

A 3-year-old girl with the diagnosis of chronic granulomatous disease (CGD) was hospitalized for bronchopneumonia and congestive heart failure. Her medical history included methylprednisolone medication for autoimmune gastric outlet obstruction. Computed tomography revealed pneumonic infiltrations and pericardial thickening. A pulsed-wave Doppler recording revealed E/A >1. During a pericardiectomy, multiple islands of thick, firm-walled, fibrinous exudate-containing, small abscess formations were observed. Histopathological evaluation of pericardial tissue revealed granulomatous inflammation. Aspergillus fumigatus was cultured from the abscess. In conclusion, development of constrictive aspergillus pericarditis should be considered in patients with CGD because immediate initiation of anti-fungal management with aggressive surgical treatment is life-saving.

Keywords: Aspergillosis, chronic granulomatous disease, constrictive pericarditis, pericardiectomy.

How to cite this article
Emrah Şişli, Yasemin Özdemir Şahan, Mehmet Fatih Ayık, Deniz Nart, Yüksel Atay. A rare complication of chronic granulomatous disease in a child: constrictive aspergillus pericarditis. Turk Kardiyol Dern Ars. 2017; 45(7): 660-663

Corresponding Author: Emrah Şişli, Türkiye
Manuscript Language: English


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